STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
inx-22Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (462 aa)    
Predicted Functional Partners:
inx-14
Innexin-14; Structural component of the gap junctions.
  
  
0.817
F54D10.5
Uncharacterized protein.
   
  
 0.715
ceh-18
Homeobox protein ceh-18; Directs gonadal sheath cell differentiation and function. Also directs gonad migration and plays a role in specifying the differentiated phenotypes of epidermal cells during postembryonic development. Plays a role in oogenesis, regulating a sheath cell signal that causes oocytes to maintain diakinesis arrest during meiosis. Negatively regulates oocyte maturation, ovulation and MAPK activation in oocytes when sperm are not available for fertilization. May be recruited by akir-1 to the promoter regions of antimicrobial peptide genes to control gene expression in [...]
      
 0.690
inx-21
Innexin; Structural component of the gap junctions. Belongs to the pannexin family.
   
  
0.670
gsa-1
G protein, Subunit Alpha.
   
  
 0.664
acy-4
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.661
Y47G6A.26
Uncharacterized protein.
      
 0.660
Y47G6A.32
Uncharacterized protein.
      
 0.660
Y14H12B.2
SPK domain-containing protein.
   
    0.639
R02F2.4
Uncharacterized protein.
   
 
 0.625
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.