STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y51A2D.14Uncharacterized protein. (54 aa)    
Predicted Functional Partners:
cpna-2
Copine family protein 2; Belongs to the copine family.
   
  
 0.816
F45G2.8
Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family.
      
 0.811
col-109
Col_cuticle_N domain-containing protein.
      
 0.807
gst-22
Glutathione S-Transferase.
      
 0.699
pyk-1
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.670
syg-2
Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites.
   
  
 0.667
acs-19
Acetyl-coenzyme A synthetase.
      
 0.610
atp-3
ATP synthase subunit.
      
 0.501
cyb-3
G2/mitotic-specific cyclin-B3; Could be involved at the G2/M (mitosis) transition (Probable). Interacts with the CDK1 and CDK2 protein kinases (Probable). G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (Probable). Plays a role during oocyte meiosis II.
      
 0.470
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.