STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plep-1PLugged Excretory Pore. (456 aa)    
Predicted Functional Partners:
K11G9.3
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.818
ZC266.1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.804
folt-2
Folate-like transporter 2; Unlike folt-1, does not appear to act as a folate transporter; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
      
 0.758
ctsa-1
Serine carboxypeptidase ctsa-4.1; Belongs to the peptidase S10 family.
      
 0.699
ugt-22
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.583
ilys-5
Invertebrate LYSozyme.
      
 0.539
aqp-8
AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.536
comp-1
Protein kinase domain-containing protein.
   
  
 0.495
unc-93
Putative potassium channel regulatory protein unc-93; May contribute to coordination of muscle contraction as regulatory subunit of a nonessential potassium channel complex. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord ; Belongs to the unc-93 family.
      
 0.475
fbxa-21
FTH domain-containing protein.
      
 0.469
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.