STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y53F4B.14Uncharacterized protein. (90 aa)    
Predicted Functional Partners:
nuo-6
NADH Ubiquinone Oxidoreductase.
   
  
 0.805
cox-17
Cytochrome OXidase assembly protein.
   
  
 0.751
suox-1
Cytochrome b5 heme-binding domain-containing protein.
      
 0.666
Y63D3A.7
L51_S25_CI-B8 domain-containing protein.
   
    0.589
cox-10
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
      
 0.547
cox-15
Cytochrome OXidase assembly protein.
      
 0.546
cox-5A
Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...]
   
  
 0.540
cox-6B
Cytochrome OXidase assembly protein.
   
  
 0.539
sco-1
SCO (Yeast Suppressor of Cytochrome Oxidase deficiency) homolog.
      
 0.478
cox-11
Cytochrome OXidase assembly protein.
   
  
 0.459
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.