STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbc-2RaBConnectin related. (1322 aa)    
Predicted Functional Partners:
fer-1
Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis.
      
 0.809
ttc-37
TeTratriCopeptide repeat domain protein related.
    
 
 0.743
rbc-1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.724
skih-2
SKI (Yeast SuperKIller) Helicase homolog.
    
 
 0.708
eef-1G
Probable elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
      
 0.668
F02E9.1
Uncharacterized protein.
    
 
 0.651
cdc-73
Cell division cycle protein 73; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification; Belongs to the CDC73 family.
    
 
 0.597
pef-1
Serine/threonine-protein phosphatase with EF-hands pef-1; Probably acts as a protein phosphatase.
    
 
 0.596
vha-11
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Has roles in embryogenesis and ovulation.
      
 0.587
leo-1
RNA polymerase-associated protein LEO1; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
   
 
 0.580
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.