node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0563.7 | K03A1.4 | B0563.7.1 | K03A1.4a.1 | Uncharacterized calcium-binding protein B0563.7. | EF-hand domain-containing protein. | 0.432 |
B0563.7 | cal-3 | B0563.7.1 | M02B7.6a.1 | Uncharacterized calcium-binding protein B0563.7. | CALmodulin related genes. | 0.409 |
B0563.7 | cal-4 | B0563.7.1 | T07G12.1a.1 | Uncharacterized calcium-binding protein B0563.7. | CALmodulin related genes. | 0.419 |
B0563.7 | cal-7 | B0563.7.1 | F40F9.8.1 | Uncharacterized calcium-binding protein B0563.7. | EF-hand domain-containing protein. | 0.660 |
B0563.7 | cmd-1 | B0563.7.1 | T21H3.3a.1 | Uncharacterized calcium-binding protein B0563.7. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | 0.442 |
B0563.7 | itr-1 | B0563.7.1 | F33D4.2a.1 | Uncharacterized calcium-binding protein B0563.7. | Inositol 1,4,5-trisphosphate receptor itr-1; Receptor for inositol 1,4,5-trisphosphate, a second messenger that regulates intracellular calcium homeostasis. Binds in vitro to both inositol 1,4,5-trisphosphate (1,4,5-InsP3) and inositol 2,4,5-trisphosphate (2,4,5-InsP3) with high affinity and does not discriminate between the phosphate at 1 or 2 position. Can also bind inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-InsP4) and inositol 4,5-bisphosphate (4,5-InsP2), but with lower affinity. Acts as a timekeeper/rhythm generator via calcium signaling, affecting the defecation cycle and pharyn [...] | 0.894 |
B0563.7 | orai-1 | B0563.7.1 | C09F5.2a.1 | Uncharacterized calcium-binding protein B0563.7. | Protein orai; Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function. Belongs to the Orai family. | 0.543 |
B0563.7 | stim-1 | B0563.7.1 | Y55B1BM.1a.1 | Uncharacterized calcium-binding protein B0563.7. | Stromal interaction molecule 1; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor which upon Ca(2+) depletion, activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, orai-1. Essential for Ca (2+) and IP3-dependent contractile activity of gonad sheath cells and spermatheca. Essential for fertility. Does not play a role in posterior body wall muscle contraction (pBoc) rhythmicity, intestinal cell oscillatory Ca(2+) signaling or intestinal ER Ca(2+) hemostasis. | 0.862 |
K03A1.4 | B0563.7 | K03A1.4a.1 | B0563.7.1 | EF-hand domain-containing protein. | Uncharacterized calcium-binding protein B0563.7. | 0.432 |
K03A1.4 | cal-1 | K03A1.4a.1 | C13C12.1b.1 | EF-hand domain-containing protein. | Calmodulin-like protein; This protein resembles calmodulin in sequence but possibly resembles troponin C in function. | 0.408 |
K03A1.4 | cal-2 | K03A1.4a.1 | C18E9.1.1 | EF-hand domain-containing protein. | CALmodulin related genes. | 0.420 |
K03A1.4 | cal-3 | K03A1.4a.1 | M02B7.6a.1 | EF-hand domain-containing protein. | CALmodulin related genes. | 0.414 |
K03A1.4 | cal-4 | K03A1.4a.1 | T07G12.1a.1 | EF-hand domain-containing protein. | CALmodulin related genes. | 0.455 |
K03A1.4 | cal-7 | K03A1.4a.1 | F40F9.8.1 | EF-hand domain-containing protein. | EF-hand domain-containing protein. | 0.664 |
K03A1.4 | cmd-1 | K03A1.4a.1 | T21H3.3a.1 | EF-hand domain-containing protein. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | 0.455 |
K03A1.4 | itr-1 | K03A1.4a.1 | F33D4.2a.1 | EF-hand domain-containing protein. | Inositol 1,4,5-trisphosphate receptor itr-1; Receptor for inositol 1,4,5-trisphosphate, a second messenger that regulates intracellular calcium homeostasis. Binds in vitro to both inositol 1,4,5-trisphosphate (1,4,5-InsP3) and inositol 2,4,5-trisphosphate (2,4,5-InsP3) with high affinity and does not discriminate between the phosphate at 1 or 2 position. Can also bind inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-InsP4) and inositol 4,5-bisphosphate (4,5-InsP2), but with lower affinity. Acts as a timekeeper/rhythm generator via calcium signaling, affecting the defecation cycle and pharyn [...] | 0.893 |
K03A1.4 | orai-1 | K03A1.4a.1 | C09F5.2a.1 | EF-hand domain-containing protein. | Protein orai; Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function. Belongs to the Orai family. | 0.543 |
K03A1.4 | stim-1 | K03A1.4a.1 | Y55B1BM.1a.1 | EF-hand domain-containing protein. | Stromal interaction molecule 1; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor which upon Ca(2+) depletion, activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, orai-1. Essential for Ca (2+) and IP3-dependent contractile activity of gonad sheath cells and spermatheca. Essential for fertility. Does not play a role in posterior body wall muscle contraction (pBoc) rhythmicity, intestinal cell oscillatory Ca(2+) signaling or intestinal ER Ca(2+) hemostasis. | 0.862 |
cal-1 | K03A1.4 | C13C12.1b.1 | K03A1.4a.1 | Calmodulin-like protein; This protein resembles calmodulin in sequence but possibly resembles troponin C in function. | EF-hand domain-containing protein. | 0.408 |
cal-1 | cal-7 | C13C12.1b.1 | F40F9.8.1 | Calmodulin-like protein; This protein resembles calmodulin in sequence but possibly resembles troponin C in function. | EF-hand domain-containing protein. | 0.440 |