node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cox-16 | cutl-26 | C24G6.8.1 | Y55F3C.7b.1 | Probable peptidyl-tRNA hydrolase 2; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis; Belongs to the PTH2 family. | ZP domain-containing protein. | 0.574 |
cutl-26 | cox-16 | Y55F3C.7b.1 | C24G6.8.1 | ZP domain-containing protein. | Probable peptidyl-tRNA hydrolase 2; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis; Belongs to the PTH2 family. | 0.574 |
cutl-26 | isw-1 | Y55F3C.7b.1 | F37A4.8.1 | ZP domain-containing protein. | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | 0.940 |
cutl-26 | lin-53 | Y55F3C.7b.1 | K07A1.12.1 | ZP domain-containing protein. | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] | 0.924 |
cutl-26 | lin-59 | Y55F3C.7b.1 | T12F5.4.1 | ZP domain-containing protein. | Probable histone-lysine N-methyltransferase lin-59; Probable histone methyltransferase (By similarity). Essential protein required to maintain expression of homeotic genes egl-5 and mab-5. May play an analogous role to the trithorax Group (trxG) proteins. TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development. May act via a modification of chromatin. | 0.631 |
cutl-26 | met-1 | Y55F3C.7b.1 | C43E11.3a.1 | ZP domain-containing protein. | Histone-lysine N-methyltransferase. | 0.590 |
cutl-26 | pqn-85 | Y55F3C.7b.1 | Y43H11AL.3a.1 | ZP domain-containing protein. | Nipped-B-like protein pqn-85; Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity). | 0.803 |
cutl-26 | pyp-1 | Y55F3C.7b.1 | C47E12.4c.3 | ZP domain-containing protein. | Inorganic pyrophosphatase 1; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. Plays a role in intestinal development and subsequent normal secretory, digestive and absorption functions. Required for larval development. | 0.655 |
cutl-26 | rba-1 | Y55F3C.7b.1 | K07A1.11.1 | ZP domain-containing protein. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.761 |
cutl-26 | set-12 | Y55F3C.7b.1 | K09F5.5.1 | ZP domain-containing protein. | Histone-lysine N-methyltransferase. | 0.590 |
cutl-26 | xnp-1 | Y55F3C.7b.1 | B0041.7.2 | ZP domain-containing protein. | Transcriptional regulator ATRX homolog; Required for embryonic development and gonadogenesis. Also, functions redundantly with the transcriptional repressor lin-35 to regulate somatic gonad development. | 0.583 |
isw-1 | cutl-26 | F37A4.8.1 | Y55F3C.7b.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | ZP domain-containing protein. | 0.940 |
isw-1 | lin-53 | F37A4.8.1 | K07A1.12.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] | 0.978 |
isw-1 | lin-59 | F37A4.8.1 | T12F5.4.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Probable histone-lysine N-methyltransferase lin-59; Probable histone methyltransferase (By similarity). Essential protein required to maintain expression of homeotic genes egl-5 and mab-5. May play an analogous role to the trithorax Group (trxG) proteins. TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development. May act via a modification of chromatin. | 0.434 |
isw-1 | met-1 | F37A4.8.1 | C43E11.3a.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Histone-lysine N-methyltransferase. | 0.404 |
isw-1 | pqn-85 | F37A4.8.1 | Y43H11AL.3a.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Nipped-B-like protein pqn-85; Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity). | 0.615 |
isw-1 | pyp-1 | F37A4.8.1 | C47E12.4c.3 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Inorganic pyrophosphatase 1; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. Plays a role in intestinal development and subsequent normal secretory, digestive and absorption functions. Required for larval development. | 0.799 |
isw-1 | rba-1 | F37A4.8.1 | K07A1.11.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.859 |
isw-1 | set-12 | F37A4.8.1 | K09F5.5.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Histone-lysine N-methyltransferase. | 0.402 |
lin-53 | cutl-26 | K07A1.12.1 | Y55F3C.7b.1 | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] | ZP domain-containing protein. | 0.924 |