STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgc-26Neur_chan_LBD domain-containing protein. (486 aa)    
Predicted Functional Partners:
lgc-28
Neur_chan_LBD domain-containing protein.
   
  
 0.840
lgc-27
Neur_chan_LBD domain-containing protein.
   
  
 0.824
lgc-24
Neur_chan_LBD domain-containing protein.
      
 0.759
acr-9
AcetylCholine Receptor.
  
0.627
acr-16
Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor.
  
0.626
acr-14
AcetylCholine Receptor.
  
0.626
lgc-46
Probable ligand-gated ion channel 46; Probable component of a ligand-gated anion channel. Negatively regulates synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. Role in synaptic vesicle release kinetics may be in association with the ligand-gated ion channel protein acc-4.
  
   
 0.616
acr-25
AcetylCholine Receptor.
  
  
0.614
acr-15
AcetylCholine Receptor.
  
 
0.602
acr-7
Acetylcholine receptor subunit alpha-type acr-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  
 
0.600
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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