STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y59A8B.12Uncharacterized protein. (118 aa)    
Predicted Functional Partners:
slr-2
Synthetic with Lin-35/Rb.
   
  
 0.702
dap-3
Mammalian cell Death Associated Protein related.
      
 0.666
nhr-268
Nuclear hormone receptor family member nhr-268; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
      
 0.666
nhr-274
NR LBD domain-containing protein.
      
 0.666
R02E12.4
Uncharacterized protein.
      
 0.660
C29A12.1
Uncharacterized protein.
   
    0.592
Y54G9A.5
Uncharacterized protein.
   
    0.592
F54D10.5
Uncharacterized protein.
   
    0.590
lab-1
Long arms of the bivalent protein 1; Involved in sister chromatid cohesion during mitosis and meiosis. In association with the gsp-2 phosphatase, it both restricts the localization and antagonizes the function of the air-2 kinase during meiosis I and mitosis to promote chromatid cohesion and spindle attachment. This in turn, drives germ cell immortality. Furthermore, may play a role in ensuring the timely assembly of the synaptonemal complex during prophase I of meiosis.
   
    0.544
nas-18
Zinc metalloproteinase nas-18; Metalloprotease.
      
 0.539
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.