STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acs-13AMP-binding domain-containing protein. (726 aa)    
Predicted Functional Partners:
acs-16
AMP-binding domain-containing protein.
  
 
 0.940
fasn-1
Carrier domain-containing protein.
  
 0.919
cpt-1
Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.910
W03F9.4
Carn_acyltransf domain-containing protein.
     
 0.906
acs-4
Fatty Acid CoA Synthetase family.
  
0.889
Y63D3A.8
TLC domain-containing protein fld-1; Regulates the composition and fluidity of the plasma membrane. Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity. Does not appear to have any effect on LCPUFA synthesis.
   
  
 0.881
ppt-1
Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides.
   
 
 0.844
iglr-2
Immunoglobulin domain and leucine-rich repeat-containing protein 2.
   
  
 0.812
acs-2
Fatty Acid CoA Synthetase family.
  
 
0.782
crls-1
Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.737
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.