STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y69A2AL.2Phospholipase A(2). (157 aa)    
Predicted Functional Partners:
T26E4.3
Uncharacterized protein.
   
  
 0.763
BE10.3
Uncharacterized protein.
      
 0.758
ipla-1
DDHD domain-containing protein.
      
 0.758
W03D8.8
Uncharacterized protein.
      
 0.692
stdh-3
Putative steroid dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
      
 0.667
ipla-3
Intracelllar PhosphoLipase A family.
   
  
 0.524
nsun-5
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.501
fut-2
Galactoside 2-alpha-L-fucosyltransferase; Selectively catalyzes the addition of fucose in alpha 1-2 linkage to Gal-beta-(1->4)-Xyl-beta-R, Gal-beta-(1->6)-GlcNAc-R, Gal- beta-(1->3)-Gal-beta-(1->4)-Glc and Gal-beta-(1->3)-Gal-beta-(1->4)- Xyl-R acceptors but not Gal-beta-(1->3)-GlcNAc-beta-(1->3)-Gal-beta- (1->4)-Glc. Unlike in mammals, unable to fucosylate Gal-beta-(1->4)- Glc-beta-R.
   
  
 0.477
sams-1
Probable S-adenosylmethionine synthase 1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family.
      
 0.461
ipla-2
Intracelllar PhosphoLipase A family.
   
  
 0.429
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.