node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ada-2 | fzy-1 | F32A5.1a.1 | ZK177.6.1 | SANT domain-containing protein. | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.432 |
ada-2 | pcaf-1 | F32A5.1a.1 | Y47G6A.6.1 | SANT domain-containing protein. | P300/CBP Associated Factor homolog. | 0.996 |
ada-2 | taf-10 | F32A5.1a.1 | K03B4.3b.3 | SANT domain-containing protein. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.986 |
ada-2 | taf-5 | F32A5.1a.1 | F30F8.8.3 | SANT domain-containing protein. | TAF (TBP-associated transcription factor) family. | 0.957 |
ada-2 | taf-9 | F32A5.1a.1 | T12D8.7.2 | SANT domain-containing protein. | TAF (TBP-associated transcription factor) family. | 0.991 |
ada-2 | trr-1 | F32A5.1a.1 | C47D12.1a.1 | SANT domain-containing protein. | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.991 |
ada-2 | usp-3 | F32A5.1a.1 | Y71A12B.9.1 | SANT domain-containing protein. | Ubiquitin carboxyl-terminal hydrolase. | 0.809 |
fzy-1 | ada-2 | ZK177.6.1 | F32A5.1a.1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | SANT domain-containing protein. | 0.432 |
fzy-1 | pcaf-1 | ZK177.6.1 | Y47G6A.6.1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | P300/CBP Associated Factor homolog. | 0.545 |
fzy-1 | taf-10 | ZK177.6.1 | K03B4.3b.3 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.570 |
fzy-1 | taf-9 | ZK177.6.1 | T12D8.7.2 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | TAF (TBP-associated transcription factor) family. | 0.570 |
fzy-1 | trr-1 | ZK177.6.1 | C47D12.1a.1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.537 |
fzy-1 | ubq-2 | ZK177.6.1 | ZK1010.1.1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.741 |
fzy-1 | usp-3 | ZK177.6.1 | Y71A12B.9.1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | Ubiquitin carboxyl-terminal hydrolase. | 0.930 |
otub-1 | ubc-13 | C25D7.8.2 | Y54G2A.31.1 | Ubiquitin thioesterase otubain-like; Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin. | Ubiquitin-conjugating enzyme E2 13; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. May be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates. May have a role in AMPA-type glutamate receptor trafficking in neurons. | 0.998 |
otub-1 | ubq-2 | C25D7.8.2 | ZK1010.1.1 | Ubiquitin thioesterase otubain-like; Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.985 |
otub-1 | usp-3 | C25D7.8.2 | Y71A12B.9.1 | Ubiquitin thioesterase otubain-like; Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin. | Ubiquitin carboxyl-terminal hydrolase. | 0.921 |
pcaf-1 | ada-2 | Y47G6A.6.1 | F32A5.1a.1 | P300/CBP Associated Factor homolog. | SANT domain-containing protein. | 0.996 |
pcaf-1 | fzy-1 | Y47G6A.6.1 | ZK177.6.1 | P300/CBP Associated Factor homolog. | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.545 |
pcaf-1 | taf-10 | Y47G6A.6.1 | K03B4.3b.3 | P300/CBP Associated Factor homolog. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.996 |