node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C53H9.3 | Y51F10.4 | C53H9.3.1 | Y51F10.4a.1 | Uncharacterized protein. | Aa_trans domain-containing protein. | 0.851 |
C53H9.3 | drag-1 | C53H9.3.1 | Y71G12B.16.1 | Uncharacterized protein. | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | 0.664 |
Y51F10.4 | C53H9.3 | Y51F10.4a.1 | C53H9.3.1 | Aa_trans domain-containing protein. | Uncharacterized protein. | 0.851 |
Y51F10.4 | drag-1 | Y51F10.4a.1 | Y71G12B.16.1 | Aa_trans domain-containing protein. | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | 0.669 |
crm-1 | dbl-1 | B0024.14b.1 | T25F10.2.1 | CRiM (Cysteine Rich motor neuron protein) homolog. | TGF_BETA_2 domain-containing protein. | 0.464 |
crm-1 | drag-1 | B0024.14b.1 | Y71G12B.16.1 | CRiM (Cysteine Rich motor neuron protein) homolog. | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | 0.735 |
crm-1 | sma-10 | B0024.14b.1 | T21D12.9a.2 | CRiM (Cysteine Rich motor neuron protein) homolog. | Leucine-rich repeats and immunoglobulin-like domains protein sma-10; Binds to the TGF-beta receptors sma-6 and daf-4, and enhances TGF-beta signaling activity in vitro. Has a role in regulation of body size. | 0.611 |
crm-1 | sma-9 | B0024.14b.1 | T05A10.1m.1 | CRiM (Cysteine Rich motor neuron protein) homolog. | SMAll. | 0.644 |
crm-1 | tsp-21 | B0024.14b.1 | C17G1.8.2 | CRiM (Cysteine Rich motor neuron protein) homolog. | Tetraspanin-21; Regulates cell fate specification in the postembryonic mesodermal M lineage and body size, probably by positively modulating BMP-like Sma/Mab signaling at the ligand-receptor level. Promotes ventral fate specification in the M lineage, probably by positively modulating lin-12/Notch signaling; Belongs to the tetraspanin (TM4SF) family. | 0.410 |
dbl-1 | crm-1 | T25F10.2.1 | B0024.14b.1 | TGF_BETA_2 domain-containing protein. | CRiM (Cysteine Rich motor neuron protein) homolog. | 0.464 |
dbl-1 | drag-1 | T25F10.2.1 | Y71G12B.16.1 | TGF_BETA_2 domain-containing protein. | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | 0.898 |
dbl-1 | sma-10 | T25F10.2.1 | T21D12.9a.2 | TGF_BETA_2 domain-containing protein. | Leucine-rich repeats and immunoglobulin-like domains protein sma-10; Binds to the TGF-beta receptors sma-6 and daf-4, and enhances TGF-beta signaling activity in vitro. Has a role in regulation of body size. | 0.761 |
dbl-1 | sma-6 | T25F10.2.1 | C32D5.2.1 | TGF_BETA_2 domain-containing protein. | Serine/threonine-protein kinase sma-6; Involved in TGF-beta pathway. May be a receptor for daf-7; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.999 |
dbl-1 | sma-9 | T25F10.2.1 | T05A10.1m.1 | TGF_BETA_2 domain-containing protein. | SMAll. | 0.949 |
dbl-1 | unc-40 | T25F10.2.1 | T19B4.7.1 | TGF_BETA_2 domain-containing protein. | Unc-40 protein. | 0.653 |
drag-1 | C53H9.3 | Y71G12B.16.1 | C53H9.3.1 | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | Uncharacterized protein. | 0.664 |
drag-1 | Y51F10.4 | Y71G12B.16.1 | Y51F10.4a.1 | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | Aa_trans domain-containing protein. | 0.669 |
drag-1 | crm-1 | Y71G12B.16.1 | B0024.14b.1 | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | CRiM (Cysteine Rich motor neuron protein) homolog. | 0.735 |
drag-1 | dbl-1 | Y71G12B.16.1 | T25F10.2.1 | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | TGF_BETA_2 domain-containing protein. | 0.898 |
drag-1 | sma-10 | Y71G12B.16.1 | T21D12.9a.2 | RGM domain family member drag-1; Probably in association with the cell surface receptor unc-40 positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway ; Belongs to the repulsive guidance molecule (RGM) family. | Leucine-rich repeats and immunoglobulin-like domains protein sma-10; Binds to the TGF-beta receptors sma-6 and daf-4, and enhances TGF-beta signaling activity in vitro. Has a role in regulation of body size. | 0.768 |