STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyr-6TYRosinase. (751 aa)    
Predicted Functional Partners:
C56G2.15
N-acetyltransferase domain-containing protein.
      
 0.808
his-53
Histone H2A.
    
 
 0.722
tyr-1
Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family.
  
  
0.710
unc-89
Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...]
   
 
 0.508
lys-1
Lysozyme-like protein 1; Involved in resistance to Gram-negative bacterium S.marcescens and to bacterium Gram-positive S.aureus infection.
   
  
 0.502
magu-2
MAGUK family; Belongs to the MAGUK family.
    
 
 0.438
magu-1
MAGUK family.
    
 
 0.407
his-5
Histone H4.
    
 
 0.405
magu-3
Guanylate kinase-like domain-containing protein.
    
 
 0.404
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.