STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mif-4MIF (Macrophage migration Inhibitory Factor) related. (121 aa)    
Predicted Functional Partners:
mif-3
MIF-like protein mif-3; Belongs to the MIF family.
      
 0.966
mif-1
MIF (Macrophage migration Inhibitory Factor) related.
      
 0.911
mif-2
MIF-like protein mif-2; Belongs to the MIF family.
      
 0.894
cpi-2
Cystatin cpi-2; Cysteine protease inhibitor which inhibits members of the peptidase C1 family. Does not inhibit asparaginyl endopeptidase. Required for the uptake and/or processing of yolk proteins during the development of oocytes, probably by regulating the catalytic activity of cysteine proteases cpl-1 and cpz-1. May play a protective role against exogenous cysteine proteases derived from soil bacteria or fungi, or rotting fruits and vegetation. Belongs to the cystatin family.
   
  
 0.815
F43G9.4
Uncharacterized protein.
      
 0.808
T28F4.4
Uncharacterized protein.
      
 0.741
cfim-1
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
  
 0.698
imp-1
IntraMembrane Protease (IMPAS) family.
      
 0.697
slc-25A42
SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.697
T28F4.5
Uncharacterized protein.
      
 0.691
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.