STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ipla-6PNPLA domain-containing protein. (546 aa)    
Predicted Functional Partners:
dif-1
Protein dif-1; Seems to play a role in the maintenance of tissue differentiation in the developing embryo, but not for its initiation.
 
      0.878
ufd-3
Ubiquitin fusion degradation protein 3 homolog; Plays a role in protein ubiquitination, sorting and degradation through its association with cdc-48.1 and/or cdc-48.2.
   
  
 0.845
C36A4.4
Probable UDP-N-acetylglucosamine pyrophosphorylase.
   
  
 0.831
gna-1
Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
   
  
 0.814
gfat-2
Glutamine-Fructose 6-phosphate AminoTransferase homolog.
   
  
 0.810
tps-2
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2; Catalyzes the production of trehalose from glucose-6- phosphate and UDP-alpha-D-glucose in a 2 step process; In the N-terminal section; belongs to the glycosyltransferase 20 family.
      
 0.803
gsy-1
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family.
   
  
 0.713
gna-2
Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
   
  
 0.708
oga-1
O-GlcNAc selective N-Acetyl-beta-D-glucosaminidase (O-GlcNAcase).
   
  
 0.699
tre-1
Trehalase.
   
  
 0.694
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.