STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sqd-1Homologous to Drosophila SQD (Squid) protein. (308 aa)    
Predicted Functional Partners:
sut-2
Zinc finger CCCH domain-containing protein 14.
    
 
 0.901
sig-7
Peptidyl-prolyl cis-trans isomerase sig-7; Probable PPIase that accelerates the folding of proteins (By similarity). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans- splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transc [...]
      
 0.816
imb-2
Importin N-terminal domain-containing protein.
   
 
 0.779
rsp-3
Probable splicing factor, arginine/serine-rich 3; Plays an essential role in embryogenesis.
  
 0.747
rsp-8
RRM domain-containing protein.
  
 0.729
Y23H5A.3
Uncharacterized protein.
      
 0.725
cey-1
CSD_1 domain-containing protein.
   
 0.712
sdz-18
BTB domain-containing protein.
   
  
 0.699
sdz-27
SKN-1 Dependent Zygotic transcript.
      
 0.699
vet-2
Very Early Transcript.
      
 0.698
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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