STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y76B12C.3Sep15_SelM domain-containing protein. (152 aa)    
Predicted Functional Partners:
scl-3
SCP domain-containing protein; Belongs to the CRISP family.
      
 0.917
Y8A9A.2
Uncharacterized protein.
      
 0.905
nas-12
Zinc metalloproteinase nas-12; Metalloprotease.
      
 0.894
wrt-3
Warthog protein 3; Intercellular signal essential for a variety of patterning events during development.
      
 0.891
phat-5
PHAryngeal gland Toxin-related.
      
 0.809
ZK596.1
DUF148 domain-containing protein.
      
 0.808
nhr-48
Nuclear hormone receptor family member nhr-48; Orphan nuclear receptor.
      
 0.760
hlh-6
Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity.
      
 0.699
F32D8.14
Protein YIPF.
   
  
 0.668
selt-1.1
Thioredoxin reductase-like selenoprotein T homolog selt-1.1; Probably has thioredoxin reductase-like oxidoreductase activity. Plays a role in regulating the oxidative stress response, and odorant and pathogenic bacteria avoidance behavior.
   
  
 0.632
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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