STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y92H12BL.1Threonylcarbamoyladenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. Belongs to the methylthiotransferase family. CDKAL1 subfamily. (425 aa)    
Predicted Functional Partners:
F35D2.6
Uncharacterized protein.
  
 
 0.711
Y92H12BL.4
Uncharacterized protein.
 
 
  
 0.678
Y92H12BL.5
Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.
 
    0.668
F20D6.11
Rieske domain-containing protein.
      
 0.651
gbh-2
Gamma Butyrobetaine Hydroxylase.
      
 0.649
mms-19
MMS19_N domain-containing protein.
   
 
 0.573
pha-2
Homeobox domain-containing protein.
      
 0.553
exos-3
KH_dom_type_1 domain-containing protein.
    
   0.512
T23B5.4
RF_PROK_I domain-containing protein.
  
  
 0.486
W03F8.3
Probable peptide chain release factor 1, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
  
  
 0.486
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.