node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F38A1.8 | uba-5 | F38A1.8.1 | T03F1.1.2 | SRP54 domain-containing protein. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates ufm-1. Required for interaction between ufm-1 and ufc-1; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. | 0.476 |
F38A1.8 | ufbp-1 | F38A1.8.1 | ZK1236.7a.1 | SRP54 domain-containing protein. | DDRGK domain-containing protein 1. | 0.475 |
cdkr-3 | odr-8 | Y113G7B.16.1 | F38A5.1a.1 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | 0.571 |
cdkr-3 | uba-5 | Y113G7B.16.1 | T03F1.1.2 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates ufm-1. Required for interaction between ufm-1 and ufc-1; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. | 0.564 |
cdkr-3 | ufbp-1 | Y113G7B.16.1 | ZK1236.7a.1 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | DDRGK domain-containing protein 1. | 0.958 |
cdkr-3 | ufc-1 | Y113G7B.16.1 | C40H1.6.1 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with ufm-1. The intermediate is formed via a thioester linkage (By similarity). | 0.598 |
cdkr-3 | ufl-1 | Y113G7B.16.1 | C06G3.9.2 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | E3 UFM1-protein ligase 1 homolog; E3 UFM1-protein ligase that mediates ufmylation of target proteins. | 0.962 |
cdkr-3 | ufm-1 | Y113G7B.16.1 | ZK652.3.1 | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer (By similarity). The so-called ufmylation requires the ufm-1-activating E1 enzyme uba-5, the ufm-1-conjugating E2 enzyme ufc- 1, and probably the ufm-1-ligase E3 enzyme ufl-1. Belongs to the UFM1 family. | 0.465 |
cpt-2 | nuaf-3 | R07H5.2a.1 | R07H5.3a.2 | Calponin-homology (CH) domain-containing protein. | NADH:Ubiquinone oxidoreductase Assembly Factor. | 0.807 |
cpt-2 | prx-14 | R07H5.2a.1 | R07H5.1.1 | Calponin-homology (CH) domain-containing protein. | Pex14_N domain-containing protein. | 0.881 |
cpt-2 | ufbp-1 | R07H5.2a.1 | ZK1236.7a.1 | Calponin-homology (CH) domain-containing protein. | DDRGK domain-containing protein 1. | 0.469 |
nuaf-3 | cpt-2 | R07H5.3a.2 | R07H5.2a.1 | NADH:Ubiquinone oxidoreductase Assembly Factor. | Calponin-homology (CH) domain-containing protein. | 0.807 |
nuaf-3 | prx-14 | R07H5.3a.2 | R07H5.1.1 | NADH:Ubiquinone oxidoreductase Assembly Factor. | Pex14_N domain-containing protein. | 0.848 |
nuaf-3 | ufbp-1 | R07H5.3a.2 | ZK1236.7a.1 | NADH:Ubiquinone oxidoreductase Assembly Factor. | DDRGK domain-containing protein 1. | 0.428 |
odr-8 | cdkr-3 | F38A5.1a.1 | Y113G7B.16.1 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | CDK5RAP3-like protein; Potential regulator of CDK5 activity. | 0.571 |
odr-8 | uba-5 | F38A5.1a.1 | T03F1.1.2 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates ufm-1. Required for interaction between ufm-1 and ufc-1; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. | 0.969 |
odr-8 | ufbp-1 | F38A5.1a.1 | ZK1236.7a.1 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | DDRGK domain-containing protein 1. | 0.945 |
odr-8 | ufc-1 | F38A5.1a.1 | C40H1.6.1 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with ufm-1. The intermediate is formed via a thioester linkage (By similarity). | 0.975 |
odr-8 | ufl-1 | F38A5.1a.1 | C06G3.9.2 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | E3 UFM1-protein ligase 1 homolog; E3 UFM1-protein ligase that mediates ufmylation of target proteins. | 0.971 |
odr-8 | ufm-1 | F38A5.1a.1 | ZK652.3.1 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer (By similarity). The so-called ufmylation requires the ufm-1-activating E1 enzyme uba-5, the ufm-1-conjugating E2 enzyme ufc- 1, and probably the ufm-1-ligase E3 enzyme ufl-1. Belongs to the UFM1 family. | 0.999 |