STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx-7Putative T-box protein 7. (335 aa)    
Predicted Functional Partners:
Y50D7A.1
F-box domain-containing protein.
      
 0.850
T28B4.1
F-box domain-containing protein.
      
 0.540
Y60A3A.8
FTH domain-containing protein.
      
 0.540
yap-1
Yes-associated protein homolog 1; Plays a role in thermal stress response and in aging.
    
  0.510
pcaf-1
P300/CBP Associated Factor homolog.
     
  0.499
T28B11.1
F-box domain-containing protein.
      
 0.461
tbx-34
Putative T-box protein 34.
  
   
0.444
sea-1
T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate.
  
   
0.435
R02C2.6
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.416
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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