node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Y71H2AM.2 | hipr-1 | Y71H2AM.2.1 | ZK370.3a.1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). | Huntington interacting protein related 1; Regulates pre-synaptic vesicle recycling at neuromuscular junctions of mechanosensory neurons. Plays a role in maintaining a normal defecation cycle; Belongs to the SLA2 family. | 0.673 |
apb-1 | apg-1 | Y71H2B.10a.1 | Y105E8A.9.1 | AP complex subunit beta. | AP-1 complex subunit gamma. | 0.999 |
apb-1 | chc-1 | Y71H2B.10a.1 | T20G5.1.1 | AP complex subunit beta. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.994 |
apb-1 | clic-1 | Y71H2B.10a.1 | T05B11.3.1 | AP complex subunit beta. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.921 |
apb-1 | dyn-1 | Y71H2B.10a.1 | C02C6.1b.1 | AP complex subunit beta. | Dynamin; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3- kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development. Belongs to the TRAFAC class dynamin-like GTPase supe [...] | 0.882 |
apb-1 | epn-1 | Y71H2B.10a.1 | T04C10.2b.1 | AP complex subunit beta. | ENTH domain-containing protein. | 0.793 |
apb-1 | hipr-1 | Y71H2B.10a.1 | ZK370.3a.1 | AP complex subunit beta. | Huntington interacting protein related 1; Regulates pre-synaptic vesicle recycling at neuromuscular junctions of mechanosensory neurons. Plays a role in maintaining a normal defecation cycle; Belongs to the SLA2 family. | 0.693 |
apb-1 | unc-11 | Y71H2B.10a.1 | C32E8.10c.1 | AP complex subunit beta. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.715 |
apg-1 | apb-1 | Y105E8A.9.1 | Y71H2B.10a.1 | AP-1 complex subunit gamma. | AP complex subunit beta. | 0.999 |
apg-1 | chc-1 | Y105E8A.9.1 | T20G5.1.1 | AP-1 complex subunit gamma. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.962 |
apg-1 | clic-1 | Y105E8A.9.1 | T05B11.3.1 | AP-1 complex subunit gamma. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.713 |
apg-1 | dyn-1 | Y105E8A.9.1 | C02C6.1b.1 | AP-1 complex subunit gamma. | Dynamin; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3- kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development. Belongs to the TRAFAC class dynamin-like GTPase supe [...] | 0.585 |
apg-1 | epn-1 | Y105E8A.9.1 | T04C10.2b.1 | AP-1 complex subunit gamma. | ENTH domain-containing protein. | 0.841 |
apg-1 | hipr-1 | Y105E8A.9.1 | ZK370.3a.1 | AP-1 complex subunit gamma. | Huntington interacting protein related 1; Regulates pre-synaptic vesicle recycling at neuromuscular junctions of mechanosensory neurons. Plays a role in maintaining a normal defecation cycle; Belongs to the SLA2 family. | 0.685 |
apg-1 | unc-11 | Y105E8A.9.1 | C32E8.10c.1 | AP-1 complex subunit gamma. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.681 |
chc-1 | apb-1 | T20G5.1.1 | Y71H2B.10a.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | AP complex subunit beta. | 0.994 |
chc-1 | apg-1 | T20G5.1.1 | Y105E8A.9.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | AP-1 complex subunit gamma. | 0.962 |
chc-1 | clic-1 | T20G5.1.1 | T05B11.3.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.999 |
chc-1 | dbn-1 | T20G5.1.1 | K08E3.4.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Drebrin-like protein. | 0.571 |
chc-1 | dyn-1 | T20G5.1.1 | C02C6.1b.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Dynamin; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3- kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development. Belongs to the TRAFAC class dynamin-like GTPase supe [...] | 0.986 |