STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugtp-1UDP-galactose translocator 1. (355 aa)    
Predicted Functional Partners:
cogc-4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function; Belongs to the COG4 family.
      
 0.806
gbf-1
SEC7 domain-containing protein.
      
 0.741
pie-1
Pharynx and intestine in excess protein 1; Maternally provided PIE-1 is required for germline cell fate determination. Functions as a repressor of RNA polymerase II-dependent gene expression in the developing germline. Required for expression of nos-2 in P4 germline blastomere cells. Inhibits the histone deacetylase activity of hda-1. Represses transcriptional activation of cdk-9 and cit-1.1, which are members of the P-TEFb complex.
   
  
 0.594
agef-1
SEC7 domain-containing protein.
   
  
 0.551
dpm-1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
   
  
 0.499
hut-1
Yeast Homolog UDP-Gal Transporter.
   
  
 0.487
syx-4
Putative syntaxin-4; Potentially involved in docking of synaptic vesicles at presynaptic active zones.
   
  
 0.468
sec-16
Protein transport protein Sec16.
      
 0.468
nstp-10
GDP-fucose transporter; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily.
   
  
 0.463
cav-1
Caveolin-1; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
      
 0.459
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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