STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZK418.2BTB domain-containing protein. (442 aa)    
Predicted Functional Partners:
C06A8.6
LRRcap domain-containing protein.
   
   0.676
ZK1248.5
DUF1248 domain-containing protein.
   
    0.637
F44G3.7
Uncharacterized protein; Belongs to the serpin family.
   
   0.633
F31E8.5
Uncharacterized protein.
   
    0.629
his-70
Histone H3.3-like type 1; Putative variant histone H3 which may replace conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
   
   0.626
C34D4.2
Serine/threonine-protein phosphatase.
   
   0.617
C09B9.2
Uncharacterized protein.
   
    0.615
C09D4.3
Protein kinase domain-containing protein.
   
    0.615
C15H7.3
Putative tyrosine-protein phosphatase C15H7.3.
   
    0.615
nkb-2
Na+/K+ ATPase, Beta subunit.
   
    0.615
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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