STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
toe-1HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family. (1650 aa)    
Predicted Functional Partners:
let-716
Uncharacterized protein.
   
 0.999
utp-20
DRIM domain-containing protein.
   
 0.999
wdr-46
WD_REPEATS_REGION domain-containing protein.
   
 0.999
F49D11.10
Uncharacterized protein.
   
 0.999
F55F8.3
Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.
   
 0.999
K05C4.5
Uncharacterized protein.
   
 0.999
T10B5.3
Utp12 domain-containing protein.
   
 0.999
nol-58
Nop domain-containing protein.
   
 0.999
Y23H5B.5
WD_REPEATS_REGION domain-containing protein.
   
 0.999
Y45F10D.7
Uncharacterized protein.
   
 0.999
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.