node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H27A22.1 | hizr-1 | H27A22.1b.1 | ZK455.6.1 | Peptidase_M28 domain-containing protein. | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | 0.636 |
H27A22.1 | zipt-7.2 | H27A22.1b.1 | H13N06.5.1 | Peptidase_M28 domain-containing protein. | Zinc transporter zipt-7.2; Zinc transporter. | 0.704 |
cdf-2 | hizr-1 | T18D3.3a.1 | ZK455.6.1 | Cation Diffusion Facilitator family. | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | 0.809 |
cdf-2 | zipt-2.3 | T18D3.3a.1 | Y54G9A.4.1 | Cation Diffusion Facilitator family. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.605 |
cdf-2 | zipt-7.2 | T18D3.3a.1 | H13N06.5.1 | Cation Diffusion Facilitator family. | Zinc transporter zipt-7.2; Zinc transporter. | 0.445 |
hizr-1 | H27A22.1 | ZK455.6.1 | H27A22.1b.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Peptidase_M28 domain-containing protein. | 0.636 |
hizr-1 | cdf-2 | ZK455.6.1 | T18D3.3a.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Cation Diffusion Facilitator family. | 0.809 |
hizr-1 | nhr-196 | ZK455.6.1 | K06B4.5.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Nuclear Hormone Receptor family. | 0.615 |
hizr-1 | pax-2 | ZK455.6.1 | K06B9.5a.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Paired domain-containing protein. | 0.619 |
hizr-1 | srw-7 | ZK455.6.1 | R08F11.5.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.557 |
hizr-1 | ttm-1 | ZK455.6.1 | Y39E4A.2b.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Zinc transporter ttm-1; Promotes excretion of zinc from intestinal cells into the intestinal lumen in response to increased dietary zinc. Involved in cadmium resistance, possibly by promoting its transport from cells. Involved in resistance to B.thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway. | 0.663 |
hizr-1 | zip-4 | ZK455.6.1 | Y44E3B.1a.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | BZIP domain-containing protein. | 0.634 |
hizr-1 | zip-8 | ZK455.6.1 | F23F12.9a.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | bZIP transcription factor 8. | 0.608 |
hizr-1 | zipt-2.3 | ZK455.6.1 | Y54G9A.4.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.707 |
hizr-1 | zipt-7.2 | ZK455.6.1 | H13N06.5.1 | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | Zinc transporter zipt-7.2; Zinc transporter. | 0.741 |
nhr-196 | hizr-1 | K06B4.5.1 | ZK455.6.1 | Nuclear Hormone Receptor family. | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | 0.615 |
nhr-196 | pax-2 | K06B4.5.1 | K06B9.5a.1 | Nuclear Hormone Receptor family. | Paired domain-containing protein. | 0.500 |
pax-2 | hizr-1 | K06B9.5a.1 | ZK455.6.1 | Paired domain-containing protein. | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | 0.619 |
pax-2 | nhr-196 | K06B9.5a.1 | K06B4.5.1 | Paired domain-containing protein. | Nuclear Hormone Receptor family. | 0.500 |
srw-7 | hizr-1 | R08F11.5.1 | ZK455.6.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated. | 0.557 |