STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZK484.4TRESlin (TRESLIN) homolog. (919 aa)    
Predicted Functional Partners:
mus-101
Uncharacterized protein.
   
  
 0.745
div-1
DNA polymerase alpha subunit B; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. Required for the distribution of pie-1 in cell divsion.
   
  
 0.708
sld-2
Uncharacterized protein.
   
  
 0.680
cht-4
Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.
      
 0.534
cht-2
CHiTinase; Belongs to the glycosyl hydrolase 18 family.
      
 0.532
his-72
Histone H3.3 type 2.
      
 0.531
cdt-1
CDT1 domain-containing protein.
   
  
 0.495
pigv-1
GPI mannosyltransferase pigv-1; Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis (By similarity). Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). Required for maintenance of epithelial integrity during embryogenesis. Belongs to the PIGV family.
   
 
 0.485
rcq-5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
    0.483
cht-1
Probable endochitinase.
   
  
 0.478
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.