STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ced-11Protein ced-11; Plays a major role in programmed cell death. (1418 aa)    
Predicted Functional Partners:
gtl-1
LSDAT_euk domain-containing protein.
   
 
 0.882
trp-2
TRP (Transient receptor potential) channel family; Belongs to the transient receptor (TC 1.A.4) family.
   
 0.849
trpa-2
TRPA cation channel homolog.
   
  
 0.815
cup-5
PKD_channel domain-containing protein.
   
 
 0.756
spe-41
TRP homologous cation channel protein.
    
 0.714
ocr-3
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
   
  
 0.709
K07F5.16
J domain-containing protein.
   
  
 0.703
ocr-1
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
   
  
 0.702
trp-4
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.641
ocr-4
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
   
  
 0.633
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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