STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gst-30Glutathione S-Transferase. (213 aa)    
Predicted Functional Partners:
gst-33
Glutathione S-Transferase.
  
 
 
0.908
gst-11
Glutathione S-Transferase; Belongs to the GST superfamily.
  
  
 
0.908
daf-41
Co-chaperone protein daf-41; Co-chaperone for hsp90/daf-21. Involved in regulation of longevity, larval entry and exit from the dauer stage of development and response to environmental cues, such as oxidative stress, in a temperature-dependent manner. Role in daf-16 and hsf-1 inhibition at elevated temperatures. Belongs to the p23/wos2 family.
   
 
 0.908
pges-2
ProstaGlandin E Synthase homolog.
     
 0.902
gst-44
Glutathione S-Transferase; Belongs to the GST superfamily.
   
 
 0.785
gst-25
Glutathione S-Transferase.
  
 
0.769
gst-4
Glutathione S-transferase 4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). May play a role in the detoxification of reactive oxygen species produced during pathogenic bacterial infection.
  
 
0.756
sodh-2
Alcohol dehydrogenase 2; Belongs to the zinc-containing alcohol dehydrogenase family.
     
 0.751
gpx-2
Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 
 0.745
gpx-1
Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 
 0.743
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.