STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZK546.14Uncharacterized protein ZK546.14. (472 aa)    
Predicted Functional Partners:
C18A3.3
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA.
   
 
 0.990
C16A3.6
Protein MAK16 homolog; Belongs to the MAK16 family.
   
   0.984
nifk-1
RRM domain-containing protein.
   
 
 0.983
rrp-1
Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA. Belongs to the RRP1 family.
   
 
 0.982
nog-1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Has a role in regulating longevity, growth and brood size. May regulate fat storage via the insulin/IGF pathway.
   
 
 0.973
F53E10.6
RRP15-like protein; Belongs to the RRP15 family.
   
 
 0.968
K12H4.3
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
 
 0.966
lpd-6
Brix domain-containing protein.
   
 
 0.953
M04F3.2
Uncharacterized protein.
   
 
 0.950
rpl-24.2
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity).
   
 
 0.943
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.