node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atn-1 | cal-7 | W04D2.1a.1 | F40F9.8.1 | AcTiniN. | EF-hand domain-containing protein. | 0.760 |
atn-1 | lev-11 | W04D2.1a.1 | Y105E8B.1d.1 | AcTiniN. | Tropomyosin isoforms a/b/d/f; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Protects actin filaments from depolymerization by unc-60 in vitro. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin. | 0.954 |
atn-1 | mup-2 | W04D2.1a.1 | T22E5.5.1 | AcTiniN. | Troponin T; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity. | 0.945 |
atn-1 | myo-2 | W04D2.1a.1 | T18D3.4.1 | AcTiniN. | Myosin-2; Muscle contraction. | 0.758 |
atn-1 | myo-3 | W04D2.1a.1 | K12F2.1.1 | AcTiniN. | Myosin-3; Essential for muscle contraction. Involved in ovulation likely by regulating the contraction of gonadal myoepithelial sheath cells. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.907 |
atn-1 | unc-15 | W04D2.1a.1 | F07A5.7a.2 | AcTiniN. | Paramyosin; Structural component of the muscle thick filaments which is involved in assembly and organization of sarcomere myofilaments. Involved in ovulation. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. Belongs to the paramyosin family. | 0.715 |
atn-1 | unc-22 | W04D2.1a.1 | ZK617.1b.1 | AcTiniN. | Twitchin; Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. Plays a role in the organization of sarcomeres in body wall muscles ; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.960 |
atn-1 | unc-54 | W04D2.1a.1 | F11C3.3.2 | AcTiniN. | Myosin-4; Required for muscle contraction. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.844 |
atn-1 | unc-89 | W04D2.1a.1 | C09D1.1b.1 | AcTiniN. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.852 |
cal-7 | atn-1 | F40F9.8.1 | W04D2.1a.1 | EF-hand domain-containing protein. | AcTiniN. | 0.760 |
cal-7 | lev-11 | F40F9.8.1 | Y105E8B.1d.1 | EF-hand domain-containing protein. | Tropomyosin isoforms a/b/d/f; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Protects actin filaments from depolymerization by unc-60 in vitro. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin. | 0.671 |
cal-7 | mup-2 | F40F9.8.1 | T22E5.5.1 | EF-hand domain-containing protein. | Troponin T; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity. | 0.736 |
cal-7 | myo-2 | F40F9.8.1 | T18D3.4.1 | EF-hand domain-containing protein. | Myosin-2; Muscle contraction. | 0.703 |
cal-7 | myo-3 | F40F9.8.1 | K12F2.1.1 | EF-hand domain-containing protein. | Myosin-3; Essential for muscle contraction. Involved in ovulation likely by regulating the contraction of gonadal myoepithelial sheath cells. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.700 |
cal-7 | unc-15 | F40F9.8.1 | F07A5.7a.2 | EF-hand domain-containing protein. | Paramyosin; Structural component of the muscle thick filaments which is involved in assembly and organization of sarcomere myofilaments. Involved in ovulation. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. Belongs to the paramyosin family. | 0.402 |
cal-7 | unc-22 | F40F9.8.1 | ZK617.1b.1 | EF-hand domain-containing protein. | Twitchin; Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. Plays a role in the organization of sarcomeres in body wall muscles ; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.715 |
cal-7 | unc-54 | F40F9.8.1 | F11C3.3.2 | EF-hand domain-containing protein. | Myosin-4; Required for muscle contraction. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.650 |
lev-11 | atn-1 | Y105E8B.1d.1 | W04D2.1a.1 | Tropomyosin isoforms a/b/d/f; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Protects actin filaments from depolymerization by unc-60 in vitro. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin. | AcTiniN. | 0.954 |
lev-11 | cal-7 | Y105E8B.1d.1 | F40F9.8.1 | Tropomyosin isoforms a/b/d/f; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Protects actin filaments from depolymerization by unc-60 in vitro. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin. | EF-hand domain-containing protein. | 0.671 |
lev-11 | mup-2 | Y105E8B.1d.1 | T22E5.5.1 | Tropomyosin isoforms a/b/d/f; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Protects actin filaments from depolymerization by unc-60 in vitro. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin. | Troponin T; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity. | 0.991 |