STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdz-37SKN-1 Dependent Zygotic transcript. (142 aa)    
Predicted Functional Partners:
abu-10
Activated in Blocked Unfolded protein response.
      
 0.741
ptr-3
SSD domain-containing protein.
      
 0.740
abu-6
Activated in Blocked Unfolded protein response.
      
 0.696
myrf-1
Myelin regulatory factor homolog 1, C-terminal; [Myelin regulatory factor homolog 1]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor homolog 1, N-terminal component that specifically activates transcription of genes involved in synaptic rewiring during nervous system maturation. [Myelin regulatory factor homolog 1, N-terminal]: Transcription factor that specifically activates expression of genes involved in synaptic rewiring during nervous system maturation. Specifically required for dorsal D (DD) GABA [...]
      
 0.667
abu-8
Activated in Blocked Unfolded protein response.
      
 0.662
abu-7
Activated in Blocked Unfolded protein response.
      
 0.660
abu-11
Activated in Blocked Unfolded protein response.
      
 0.660
fbxa-21
FTH domain-containing protein.
      
 0.624
nep-26
NEPrilysin metallopeptidase family.
      
 0.624
ZK673.5
Uncharacterized protein ZK673.5.
   
   
0.592
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.