STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lron-2ELRR (Extracellular Leucine-Rich Repeat) ONly. (575 aa)    
Predicted Functional Partners:
iglr-2
Immunoglobulin domain and leucine-rich repeat-containing protein 2.
      
 0.805
lat-1
Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    
   0.715
mec-8
Mec-8 protein.
      
 0.661
T10E10.4
Uncharacterized protein.
   
   0.586
F59B10.3
Uncharacterized protein F59B10.3.
   
    0.538
abu-14
Activated in Blocked Unfolded protein response.
   
   0.508
lron-15
ELRR (Extracellular Leucine-Rich Repeat) ONly.
  
  
0.491
abu-11
Activated in Blocked Unfolded protein response.
   
   0.486
T25E4.1
Uncharacterized protein T25E4.1.
   
   0.475
pan-1
P-granule-associated novel protein 1; Regulates diverse developmental processes including larval molting and gonad maturation.
  
  
0.463
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.