node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F53H4.6 | ama-1 | F53H4.6.1 | F36A4.7.2 | Helicase C-terminal domain-containing protein. | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | 0.948 |
F53H4.6 | csa-1 | F53H4.6.1 | D2013.3.1 | Helicase C-terminal domain-containing protein. | Cockayne Syndrome complementation group A homolog. | 0.629 |
F53H4.6 | cul-4 | F53H4.6.1 | F45E12.3.1 | Helicase C-terminal domain-containing protein. | Cullin-4; Component of cullin-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. In association with ddb-1 directs ubiquitination of cdt-1 during S phase and is required for restraining DNA rereplication. Probably is involved in ubiquitination of cki-1. | 0.753 |
F53H4.6 | ddb-1 | F53H4.6.1 | M18.5.1 | Helicase C-terminal domain-containing protein. | DNA damage-binding protein 1; Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity). Promotes the degradation of the replication licensing factor cdt-1 during S-phase, thereby preventing rereplication of DNA during a single round of cell division. | 0.896 |
F53H4.6 | gtf-2H1 | F53H4.6.1 | R02D3.3a.1 | Helicase C-terminal domain-containing protein. | General Transcription Factor homolog. | 0.604 |
F53H4.6 | uvs-1 | F53H4.6.1 | ZK742.2.1 | Helicase C-terminal domain-containing protein. | UV-stimulated scaffold protein A homolog; Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes (By similarity). Belongs to the UVSSA family. | 0.672 |
F53H4.6 | xpa-1 | F53H4.6.1 | K07G5.2.1 | Helicase C-terminal domain-containing protein. | XPA_C domain-containing protein. | 0.908 |
F53H4.6 | xpc-1 | F53H4.6.1 | Y76B12C.2.1 | Helicase C-terminal domain-containing protein. | XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog. | 0.500 |
ama-1 | F53H4.6 | F36A4.7.2 | F53H4.6.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | Helicase C-terminal domain-containing protein. | 0.948 |
ama-1 | csa-1 | F36A4.7.2 | D2013.3.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | Cockayne Syndrome complementation group A homolog. | 0.553 |
ama-1 | csb-1 | F36A4.7.2 | F53H4.1.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | CSB (Cockayne Syndrome B) homolog. | 0.898 |
ama-1 | cul-4 | F36A4.7.2 | F45E12.3.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | Cullin-4; Component of cullin-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. In association with ddb-1 directs ubiquitination of cdt-1 during S phase and is required for restraining DNA rereplication. Probably is involved in ubiquitination of cki-1. | 0.721 |
ama-1 | ddb-1 | F36A4.7.2 | M18.5.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | DNA damage-binding protein 1; Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity). Promotes the degradation of the replication licensing factor cdt-1 during S-phase, thereby preventing rereplication of DNA during a single round of cell division. | 0.871 |
ama-1 | gtf-2H1 | F36A4.7.2 | R02D3.3a.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | General Transcription Factor homolog. | 0.964 |
ama-1 | uvs-1 | F36A4.7.2 | ZK742.2.1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | UV-stimulated scaffold protein A homolog; Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes (By similarity). Belongs to the UVSSA family. | 0.696 |
csa-1 | F53H4.6 | D2013.3.1 | F53H4.6.1 | Cockayne Syndrome complementation group A homolog. | Helicase C-terminal domain-containing protein. | 0.629 |
csa-1 | ama-1 | D2013.3.1 | F36A4.7.2 | Cockayne Syndrome complementation group A homolog. | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | 0.553 |
csa-1 | csb-1 | D2013.3.1 | F53H4.1.1 | Cockayne Syndrome complementation group A homolog. | CSB (Cockayne Syndrome B) homolog. | 0.974 |
csa-1 | cul-4 | D2013.3.1 | F45E12.3.1 | Cockayne Syndrome complementation group A homolog. | Cullin-4; Component of cullin-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. In association with ddb-1 directs ubiquitination of cdt-1 during S phase and is required for restraining DNA rereplication. Probably is involved in ubiquitination of cki-1. | 0.843 |
csa-1 | ddb-1 | D2013.3.1 | M18.5.1 | Cockayne Syndrome complementation group A homolog. | DNA damage-binding protein 1; Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity). Promotes the degradation of the replication licensing factor cdt-1 during S-phase, thereby preventing rereplication of DNA during a single round of cell division. | 0.869 |