STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbn-1FiBrilliN homolog. (2781 aa)    
Predicted Functional Partners:
noah-2
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
 
 0.914
let-4
Leucine-rich repeat-containing protein let-4; Required for apical extracellular matrix organization and epithelial junction maintenance.
   
 
 0.875
sym-1
SYM-1 protein.
   
 
 0.874
lpr-3
LiPocalin-Related protein.
   
  
 0.832
mlt-11
Uncharacterized protein.
   
 
 0.752
noah-1
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
 
0.733
egg-6
Leucine-rich repeat-containing protein egg-6; Required for apical extracellular matrix organization and epithelial junction maintenance.
    
 
 0.727
let-653
Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development.
   
  
 0.721
let-805
Myotactin form B.
   
 
 0.640
qua-1
Protein qua-1; Required for cuticle shedding and normal alae morphology and localization, and subsequently larval development.
   
 
 0.632
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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