STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-26DeHydrogenases, Short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)    
Predicted Functional Partners:
T22B7.7
Uncharacterized protein.
  
 
 0.928
pks-1
PolyKetide Synthase.
  
 0.840
C05C10.3
Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.804
cyp-33A1
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
 
 0.760
cyp-34A2
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
 
 0.735
ttr-44
TransThyretin-Related family domain.
   
 
 0.726
ugt-41
UDP-GlucuronosylTransferase.
   
 
 0.708
ugt-43
UDP-GlucuronosylTransferase.
    
 
 0.707
ugt-51
UDP-GlucuronosylTransferase.
    
 
 0.706
ugt-14
UDP-GlucuronosylTransferase.
    
 
 0.705
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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