STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZK829.7PKS_ER domain-containing protein. (372 aa)    
Predicted Functional Partners:
pks-1
PolyKetide Synthase.
  
 0.859
F32D1.5
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
  
  
 0.837
anat-1
AANAT (Arylalkylamine N-AcetylTransferase) homolog.
   
 
 0.828
ZK228.3
Acetyltransf_18 domain-containing protein.
   
  
 0.809
moc-2
MoCF_biosynth domain-containing protein.
  
  
 0.808
pes-9
M20_dimer domain-containing protein.
   
  
 0.803
F20D6.11
Rieske domain-containing protein.
  
  
 0.780
F20G2.2
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.746
gspd-1
Glucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.
   
  
 0.732
hxk-1
Phosphotransferase; Belongs to the hexokinase family.
   
 
 0.715
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.