STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zhit-3HIT-type domain-containing protein. (455 aa)    
Predicted Functional Partners:
H27A22.1
Peptidase_M28 domain-containing protein.
      
 0.884
nol-58
Nop domain-containing protein.
   
 
 0.865
zhit-1
HIT-type domain-containing protein.
   
  
 0.769
ZK1127.4
Protein BCCIP homolog; Belongs to the BCP1 family.
   
  
 0.730
tftc-5
Transcription Factor ThreeC subunit (GTF3C homolog).
   
  
 0.719
sin-3
Paired amphipathic helix protein sin-3; Probable transcriptional repressor required for the deposition of dimethylated 'Lys-9' of histone H3 (H3K9me2) on asynapsed chromosome pairs (both autosomes and sex chromosomes) during meiosis, but this does not seem to solely affect the transcriptional status. Plays a role in ray fusion and patterning in the male tail, and this may be through activity of the histone deacetylase complex (HDAC).
   
  
 0.702
C17E4.6
YL1_C domain-containing protein.
   
  
 0.700
Y23H5B.6
RNA helicase.
   
  
 0.696
sumv-1
Protein sumv-1; Nuclear factor that influences the activity of genes involved in vulval development.
   
  
 0.685
phf-15
PHd Finger family.
   
  
 0.668
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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