STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolBUnannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa)    
Predicted Functional Partners:
pal
Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 0.998
tolR
Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
 0.989
tolQ
Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
  
 0.983
ygbF
Unannotated protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.969
ompF
Unannotated protein; Belongs to the Gram-negative porin family.
  
 
 
 0.912
ompC
Unannotated protein; Belongs to the Gram-negative porin family.
  
 
 
 0.912
ompA
Unannotated protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 0.896
yfiB
Unannotated protein.
  
 0.851
yiaD
Unannotated protein.
  
 0.851
BZ172_27595
Unannotated protein.
  
 0.826
Your Current Organism:
Shigella sonnei
NCBI taxonomy Id: 216599
Other names: S. sonnei 53G, Shigella sonnei 53G, Shigella sonnei str. 53G
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.