STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0K0DZY0Uncharacterized protein. (125 aa)    
Predicted Functional Partners:
A0A0K0E3R9
Uncharacterized protein.
   
 0.979
A0A0K0EJX5
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.963
A0A0K0E6S3
Uncharacterized protein.
    
 0.951
A0A0K0EEL5
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.946
A0A0K0EPS9
ERCC4 domain-containing protein.
    
 0.946
A0A0K0E365
Uncharacterized protein.
   
 0.933
A0A0K0EHC7
DNA helicase; Belongs to the MCM family.
   
 0.931
A0A0K0ECP0
KH type-2 domain-containing protein; Belongs to the MRE11/RAD32 family.
   
 0.924
A0A0K0ERL2
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.919
A0A0K0EBR6
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.905
Your Current Organism:
Strongyloides stercoralis
NCBI taxonomy Id: 6248
Other names: S. stercoralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.