STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0K0E5V0Autophagy_act_C domain-containing protein. (170 aa)    
Predicted Functional Partners:
A0A0K0E9B8
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.958
A0A0K0EDT2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
   
 0.946
A0A0K0DY45
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.883
A0A0K0E309
E2_bind domain-containing protein.
   
 0.777
A0A0K0DXL6
ThiF domain-containing protein.
   
 0.771
A0A0K0EHP1
SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.
   
 0.771
A0A0K0EMY8
Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...]
   
 0.771
A0A0K0ETH8
ThiF domain-containing protein.
   
 0.771
A0A0K0DT51
WD_REPEATS_REGION domain-containing protein.
     
 0.725
A0A0K0E4C5
Autophagy-related protein 3.
    
 
 0.690
Your Current Organism:
Strongyloides stercoralis
NCBI taxonomy Id: 6248
Other names: S. stercoralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.