STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0K0ENA2Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (351 aa)    
Predicted Functional Partners:
A0A0K0DYT9
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
A0A0K0EKS3
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
A0A0K0E091
Dihydrolipoyl dehydrogenase.
 
 0.997
A0A0K0DSJ4
Lipoyl-binding domain-containing protein.
 
 0.993
A0A0K0EJZ9
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.988
A0A0K0EF63
Uncharacterized protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.948
A0A0K0EIB6
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.948
A0A0K0E9Q4
Citrate synthase; Belongs to the citrate synthase family.
  
 0.927
A0A0K0E926
Transket_pyr domain-containing protein.
   
 0.910
A0A0K0DV03
Protein-serine/threonine kinase.
    
 0.895
Your Current Organism:
Strongyloides stercoralis
NCBI taxonomy Id: 6248
Other names: S. stercoralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.