STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0K0EPA5E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2082 aa)    
Predicted Functional Partners:
A0A0K0E0H0
HECT domain-containing protein.
   
 0.991
A0A0K0E1T1
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.866
A0A0K0ECP1
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.866
A0A0K0DVR3
Uncharacterized protein.
   
 0.846
A0A0K0EHJ8
Ubiquitin-like domain-containing protein.
   
 0.761
A0A0K0EMD9
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.716
A0A0K0EQZ8
Ubiquitin-like domain-containing protein.
   
 0.716
A0A0K0DVZ3
RING-type domain-containing protein.
   
 0.702
A0A0K0EAP0
Uncharacterized protein.
   
 
 0.667
A0A0K0EMG9
Uncharacterized protein.
   
 0.661
Your Current Organism:
Strongyloides stercoralis
NCBI taxonomy Id: 6248
Other names: S. stercoralis
Server load: low (28%) [HD]