node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW93389.1 | EEW93395.1 | HMPREF0446_00271 | HMPREF0446_00277 | Hypothetical protein. | Hemolysin TlyA family protein. | 0.586 |
EEW93389.1 | folD | HMPREF0446_00271 | HMPREF0446_00273 | Hypothetical protein. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.597 |
EEW93389.1 | nusB | HMPREF0446_00271 | HMPREF0446_00272 | Hypothetical protein. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.870 |
EEW93389.1 | xseA | HMPREF0446_00271 | HMPREF0446_00274 | Hypothetical protein. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.588 |
EEW93395.1 | EEW93389.1 | HMPREF0446_00277 | HMPREF0446_00271 | Hemolysin TlyA family protein. | Hypothetical protein. | 0.586 |
EEW93395.1 | folD | HMPREF0446_00277 | HMPREF0446_00273 | Hemolysin TlyA family protein. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.787 |
EEW93395.1 | nusB | HMPREF0446_00277 | HMPREF0446_00272 | Hemolysin TlyA family protein. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.722 |
EEW93395.1 | xseA | HMPREF0446_00277 | HMPREF0446_00274 | Hemolysin TlyA family protein. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.827 |
fmt | folD | HMPREF0446_01316 | HMPREF0446_00273 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.980 |
fmt | nusB | HMPREF0446_01316 | HMPREF0446_00272 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.770 |
fmt | rpoZ | HMPREF0446_01316 | HMPREF0446_01314 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.529 |
folD | EEW93389.1 | HMPREF0446_00273 | HMPREF0446_00271 | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Hypothetical protein. | 0.597 |
folD | EEW93395.1 | HMPREF0446_00273 | HMPREF0446_00277 | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Hemolysin TlyA family protein. | 0.787 |
folD | fmt | HMPREF0446_00273 | HMPREF0446_01316 | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.980 |
folD | nusB | HMPREF0446_00273 | HMPREF0446_00272 | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.925 |
folD | xseA | HMPREF0446_00273 | HMPREF0446_00274 | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.904 |
nusA | nusB | HMPREF0446_00314 | HMPREF0446_00272 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.796 |
nusA | rpoA | HMPREF0446_00314 | HMPREF0446_01017 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
nusA | rpoB | HMPREF0446_00314 | HMPREF0446_01625 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
nusA | rpoZ | HMPREF0446_00314 | HMPREF0446_01314 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.829 |