Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGFBRAP1Transforming growth factor-beta receptor-associated protein 1. (825 aa)    
Predicted Functional Partners:
Vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
 0.998
vps-11-2
Vacuolar protein sorting-associated protein 11-like protein.
   
 0.997
vps-33.1
Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.997
vps18
Vacuolar protein sorting-associated protein 18-like protein.
   
 0.997
vps-41
Vacuolar protein sorting-associated protein 41-like protein.
   
 0.996
VPS8
Vacuolar protein sorting-associated protein 8-like protein.
   
 0.996
vps-11
Vacuolar protein sorting-associated protein 11-like protein.
   
 0.989
RAB5B
Ras-related protein Rab-5B.
    
 0.987
RAB7A
Ras-related protein Rab-7a.
    
 0.981
Vps39
Vam6/Vps39-like protein.
    
 
 0.966
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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