STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC5DNA repair protein complementing XP-G cell. (103 aa)    
Predicted Functional Partners:
pcn-1
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.943
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
   
 0.938
ERCC6
DNA excision repair protein ERCC-6.
  
 0.927
ERCC2
TFIIH basal transcription factor complex helicase XPD subunit.
  
 0.918
mre-11
Double-strand break repair protein mre-11; Belongs to the MRE11/RAD32 family.
  
 0.895
ERCC6-2
DNA excision repair protein ERCC-6.
  
 0.875
T16H12.4
General transcription factor IIH subunit.
    
 0.868
FANCM
Fanconi anemia group M protein.
   
 0.865
mus81
Crossover junction endonuclease MUS81.
   
 0.861
F12F6.7
Putative DNA polymerase delta small subunit.
  
 0.859
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.