STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y106G6E.45-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (220 aa)    
Predicted Functional Partners:
MTHFD1
C-1-tetrahydrofolate synthase, cytoplasmic.
   
 0.954
mel-32
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.949
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
 0.947
ATIC
Bifunctional purine biosynthesis protein PURH.
    
 0.864
ATIC-2
Bifunctional purine biosynthesis protein PURH.
    
 0.864
dhs-27-8
Putative oxidoreductase dhs-27; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.805
let-767
Very-long-chain 3-oxooacyl-coA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.805
dhs-5
Putative oxidoreductase dhs-5.
    
  0.805
F53F4.10
Putative NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial.
    
  0.799
F53F4.10-2
Putative NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial.
    
  0.799
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.