STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bre1-2E3 ubiquitin protein ligase. (576 aa)    
Predicted Functional Partners:
leo1
RNA polymerase-associated protein LEO1.
   
 0.977
ubc-1
Ubiquitin-conjugating enzyme E2 1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.930
Tcan_17505
Uncharacterized protein.
    
 0.930
Tcan_06713
Uncharacterized protein.
    
 0.930
Bre1
E3 ubiquitin protein ligase.
 
     0.924
CDC73
Parafibromin.
   
 0.893
Tcan_14801
Uncharacterized protein.
    
 0.889
paf1
RNA polymerase II-associated factor 1-like protein.
    
 0.883
ctr9
RNA polymerase-associated protein CTR9-like protein.
   
 0.856
Tcan_17768
WW domain-containing protein.
   
 0.838
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.