STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (677 aa)    
Predicted Functional Partners:
mcm-5
DNA helicase; Belongs to the MCM family.
   
 0.999
mmcm3
DNA helicase; Belongs to the MCM family.
   
 0.999
Orc5
Origin recognition complex subunit 5.
   
 0.999
mcm2
DNA helicase; Belongs to the MCM family.
  
 0.999
Cdc6
Cell division control protein 6-like protein.
  
0.999
mcm4-a
DNA helicase; Belongs to the MCM family.
   
 0.999
mcm7
DNA helicase; Belongs to the MCM family.
   
 0.999
ORC4
Origin recognition complex subunit 4.
   
 0.999
Cdt1
DNA replication factor Cdt1.
   
 0.998
cdt1
DNA replication factor Cdt1.
   
 0.998
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.