STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (246 aa)    
Predicted Functional Partners:
let-23
Receptor protein-tyrosine kinase.
   
 0.915
fyn
Tyrosine-protein kinase Fyn.
   
 0.870
fyn-2
Tyrosine-protein kinase Fyn.
   
 0.870
Ephb1
Ephrin type-B receptor 1.
    
 0.828
Hsp90b1
Endoplasmin.
    
 0.792
MATK
Megakaryocyte-associated tyrosine-protein kinase.
   
 0.781
HSP90AA1
Heat shock protein HSP 90-alpha.
   
 0.777
HSP90AB1
Heat shock cognate protein HSP 90-beta.
   
 0.777
tag-165
Putative methionine synthase reductase.
    
 0.748
POR
NADPH--cytochrome P450 reductase.
    
 0.748
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.